They are not normally severe, but they do exist.. (2019). Bao PP, Lu W, Cui Y, et al. A number of cellular and humoral immune parameters were tested. For some time, cancer researchers have considered alpha-amanitin, the toxin derived from "death cap" mushrooms, as a possible cancer treatment. preparations. There are many other species of Trametes, some of which are difficult to distinguish from turkey tail. Since the earliest reports of clinical benefits, other investigators have sought to define the mechanism of PSKs beneficial action. It was also revered in Japanese culture. Analytical studies have examined the relative amounts of the different triterpenes in fruiting bodies, as well as in mycelial preparations. Guggenheim AG, et al. You can learn more about how we ensure our content is accurate and current by reading our. The researchers also found the two extracts together could even enhance the effectiveness of a drug often used to treat colorectal cancers, 5-fluorouracil. Another retrospective analysis of nonrandomized data evaluated 254 patients with gastric carcinoma undergoing curative surgery with postoperative adjuvant treatment in Japan. : Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles. Although the content of PDQ documents can be used freely as text, it cannot be identified as an NCI PDQ cancer information summary unless it is presented in its entirety and is regularly updated. The lipid component was primarily linoleic acid, with smaller amounts of other fatty acids.[9]. An increase in peripheral blood NK cells after therapy was observed in the PSK-treated group compared with the control group. Upton R, ed. Together, the two mushroom extracts demonstrated the ability to stop cancer cells from spreading. In traditional Asian medicine, turkey tail mushrooms have often been brewed as a tea. These mushrooms may also provide other benefits, including: Research has shown that having a healthy colony of bacteria in the gut can help prevent disease and support the immune system. Biochem Biophys Res Commun 330 (1): 46-52, 2005. Depending on the outcomes of ongoing research, there may be even more options in the future if your doctor thinks it might help you recover from cancer. This type of cancer develops. In one 2019 study, a team of researchers reviewed 23 clinical trials involving more than 4,200 patients. It is used by contemporary Chinese physicians to support immune function in patients undergoing chemotherapy or radiation therapy for cancer, among other uses. Although these results are promising, people with cancer shouldnt try turkey tail before consulting with their oncologist. Board members will not respond to individual inquiries. PSP may also stimulate the immune system, and PSK is approved in Japan as an adjuvant treatment for cancer. : Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer. Yoshitani S, Takashima S: Efficacy of postoperative UFT (Tegafur/Uracil) plus PSK therapies in elderly patients with resected colorectal cancer. Turkey tail mushroom (Trametes Versicolor) has over 600 studies and 24 human clinical trials and appears in herbal texts dating back to the 16th century. In a subset analysis of patients with more than seven involved lymph nodes (pN3), the 5-year OS rate was significantly higher in the PSK group (47.8%) than that in the control group (22.8%; P = .0317). [25] The 10-year survival was significantly better for patients treated with PSK, with a hazard ratio of 0.3. After reviewing 20 years of data, the investigators stratified patients on the basis of the ratio of their granulocytes to lymphocytes (G/L), believing that G/L ratios above 2.0 would predict responders. the literature and does not represent a policy statement of NCI or NIH. A 2015 review of 11 clinical trials and an additional 17 preclinical studies found that using PSK from the Trametes versicolor mushrooms helped lung cancer patients who underwent radiation treatment live longer. Turkey Tail Mushroom Beyond Conventional Cancer Therapies Turkey Tail Mushroom Information Expanded and updated content from this page has been moved to the Turkey Tail Mushroom page on the new CancerChoices website. It has recently been pointed out that Ganoderma products derived from mycelium grown on different grain substrates contain large amounts of alpha-glucans derived from the substrate, compared with the fruiting body and its extracts, which are entirely beta-glucan in nature. Whats the Relationship Between Selenium and Breast Cancer? The information in these summaries should not be used as a basis for insurance reimbursement determinations. (2013). : Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-beta1 from prostate cancer cells. Learn. People with well-controlled metastatic cancer can. The 3-year survival rate was 62.2% in the 10 patients who received PSK and 12.5% in the 11 patients who received UFT alone (P = .038). Ying J, Mao X, Ma Q, et al. Miller RM, Taunton J: Targeting protein kinases with selective and semipromiscuous covalent inhibitors. Treatment with PSK was well tolerated, with good compliance. Theyre very common in the United States, and theyre pretty hardy, too. Jiang J, Grieb B, Thyagarajan A, et al. Carcinogenesis 29 (1): 147-56, 2008. Int J Nanomedicine 9: 109-19, 2014. Hsieh TC, Wu JM: Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by the combination of Coriolus versicolor and Ganoderma lucidum. [22,23], A retrospective study of the survival of 63 patients with colorectal cancer who were older than 70 years and treated with UFT with or without PSK included 24 patients who received UFT plus PSK. maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ Cancer Information for Health Professionals pages. This lack of purity of the products under study may account for some of the overlap of biological activities attributed to the individual components. I believe they have extracts as well as capsules, and they are very knowledgeable. The safety record for PSK is well established in Japan. The first line of treatment for breast cancer is chemotherapy, but a limited amount of research has examined whether or not turkey tail extract may be helpful during or after this treatment. Turkey tail mushrooms are generally considered safe and possibly even helpful. Patients were monitored for 5 to 7 years. Both groups underwent repeat colonoscopy at 12 months. Benson, KF et al. P. Karst and Ganoderma sinense Zhao, Xu et Zhang. [21] Patients were randomly assigned to receive either chemotherapy with mitomycin-C plus oral tegafur (also known as futraful) with (n = 377) or without (n = 374) PSK 3 g/d. Oxidative . Kono K, Kawaguchi Y, Mizukami Y, et al. Many of the studies are retrospective, which means data is gathered afterward from patients medical records. Some evidence suggests that PSP. A study published in 1994 first suggested the clinical benefit of adjuvant PSK for patients who underwent curative resection of gastric cancer in Japan. This includes the full genome sequence of G. A meta-analysis of randomized, centrally assigned, prospective clinical trials of adjuvant therapy with PSK published between 1980 and 2004 identified three clinical trials that met selection criteria covering 1,094 patients. Mushrooms can strengthen the immune system Although some study results are promising, turkey tail cant replace anticancer drugs. Small amounts of galactose, mannose, and arabinose have also been detected in the hydrolysate. The glycoprotein molecules are composed of a main chain beta- (1,4) glucan with beta- (1,3)- and beta- (1,6)-linked side chains. It can also be consumed in powder form or even made into capsules. There are hundreds of different kinds of mushrooms. Mushrooms have an established history of use in traditional oriental therapies. One review included preclinical studies conducted in Any comments or questions about the summary content should be submitted to Cancer.gov through the NCI website's Email Us. J Chromatogr B Analyt Technol Biomed Life Sci 941: 90-9, 2013. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH). There are many types of rare cancer. Neurosci Lett 448 (1): 62-6, 2008. [15] Thirty patients with stage II or III rectal cancer who were treated with S-1 and external-beam radiation therapy were randomly assigned to receive either the standard regimen or standard regimen plus PSK. The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro. In Japan, PSK is an . The activity is generally considered to be caused by the presence of high-molecular-weight polysaccharides (beta-glucans) in the mushrooms, although other constituents may also be involved. The treatment group was administered 1.5 g/d of MAK for 12 months. Celebrating 10 Years of Bastyr University San Diego. Find information and resources for current and returning patients. The best-studied Ganoderma polysaccharides possess mostly 1,3- and 1,4-glycosidic linkages, which are of high molecular weight. PSP from turkey tail extract may inhibit colon cancer cell growth, according to some research. link.springer.com/article/10.1186/s12906-019-2681-7, accp1.onlinelibrary.wiley.com/doi/abs/10.1177/009127000204200904, journals.sagepub.com/doi/full/10.1177/1534735415572883, ncbi.nlm.nih.gov/pmc/articles/PMC4684115/, link.springer.com/chapter/10.1007/978-981-13-6382-5_7, spandidos-publications.com/10.3892/ijmm.2013.1378, ncbi.nlm.nih.gov/pmc/articles/PMC6010034/, ncbi.nlm.nih.gov/pmc/articles/PMC6367522/, ncbi.nlm.nih.gov/pmc/articles/PMC2845472/, Curing Cancer: Newer Treatments to Keep an Eye On, Cancer Treatment at Home: What to Ask Your Doctor, Pancreatic Cancer May be Caused by This Killer Protein, What to Know About Cancer in the Lymph Nodes of Your Neck. Turkey tail mushroom grows on stumps and the decomposing wood of trees. Hsieh TC, et al. [21-30] Studies of the cellular pathway by which G. lucidum triterpenoids produce cytotoxicity have generally implicated apoptosis pathways, both the intrinsic or mitochondrial pathway [21,23-25,27] and the extrinsic or death receptor pathway. How is PSK given or taken? It contains polysaccharide peptide (PSP) and polysaccharide krestin (PSK), which are used as medicine. These mushrooms have been around for hundreds of years, says Santhosshi Narayanan, M.D., a physician in MD Andersons Integrative Medicine Center. J Ethnopharmacol 139 (2): 582-9, 2012. Cheng CR, Yang M, Yu K, et al. After skin cancer, breast cancer is the most common cancer in women in the U.S., according to the ACS. Medicinal mushrooms (PDQ)Health professional version. (2017). Ganopoly was administered as 1,800 mg capsules 3 times daily before meals for 12 weeks. Additionally, they found that the preparation was well tolerated by the participants in the study. Weng CJ, Chau CF, Hsieh YS, et al. turkey tail shiitake Shiitake mushrooms are the only one of these that can easily be bought whole in grocery stores. Food Chem 214: 383-92, 2017. Effects of Consuming Turkey Tail Mushrooms | Cancer Treatment When consumed in minor amounts, turkey tail mushrooms are generally harmless. Learn about clinical trials at MD Anderson and search our database for open studies. What are the potential health benefits of turkey tailmushrooms? PSK is not a homogeneous substance, with a range of molecular weights averaging 9.4 kDa (range 5-300 kDa). The mean duration of follow-up was 49 months. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Learn about how GcMAF works. If you have questions about MD Andersons appointment process, our information page may be the best place to start. : Metabolite identification of crude extract from Ganoderma lucidum in rats using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Can mushrooms help during cancer treatment? For centuries, people have used these mushrooms also known as Trametes versicolor or Coriolus versicolor as a health supplement. The authors concluded that PSK should be added to standard chemotherapy for gastric cancer patients who undergo curative gastrectomy. All rights reserved. Expert Opin Investig Drugs 22 (8): 981-92, 2013. (2013) Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by the combination of Coriolus versicolor and Ganoderma lucidum. Proceedings of the 19th Congress of the International Society Looking at the past, present, and future of Bastyr San Diego as we celebrate 10 years. : Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum. You can add a little turkey tail mushroom powder to a smoothie or make a broth with it. There were no significant differences between groups in patient demographics or tumor characteristics at baseline. Because turkey tail is a fungus, anyone with a mushroom or mold allergy should not use it. Torkelson CJ, Sweet E, Martzen MR, et al. An increasing number of men with prostate cancer are choosing active surveillance over surgery or radiation, a new study shows. Log in to our secure, personalized website to manage your care (formerly myMDAnderson). Phytochemistry 114: 66-101, 2015. These investigators had previously noted that a high CD57-positive cell count was an indicator of poor prognosis in patients with advanced gastric cancer, leading them to suggest that PSK may improve overall survival (OS) partly by inhibiting CD57-positive T cells. Coriolus (trametes) Versicolor (Turkey Tail) Over 400 in vitro and animal studies of Coriolus versicolor extract have demonstrated that it stimulates the immune system, inhibits the growth of cancer cells, and acts as a strong antioxidant. This summary is written and maintained by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board, which is Cell Physiol Biochem 33 (2): 289-99, 2014. Ikuzawa M, Matsunaga K, Nishiyama S, et al. Always ask a doctor before taking any supplements. : Genome sequence of the model medicinal mushroom Ganoderma lucidum. The 5-year OS rates were 67.9% in the PSK group and 61.8% in the control group (P = .053). PSK has been used as an adjunctive cancer treatment in thousands of patients since the mid-1970s. Proceed with caution and talk with a healthcare professional about any supplements youre thinking of taking. How is PSK given or taken? A 2012 study followed up on this call for research. For example, a review of eight studies that included more than 8,000 people with gastric cancer found that adding PSK to their chemotherapy helped them live longer. For 82 MHC expressionnegative patients with lymph node status of pN2 or greater, the RFS rates were 65% for the PSK group and 34% for the chemotherapy-only groupa significant difference with no P value offered. : Total triterpenoids from Ganoderma Lucidum suppresses prostate cancer cell growth by inducing growth arrest and apoptosis. And there are also mushrooms that decrease inflammatory compounds, which is helpful for cancer patients.. [10] Beta-glucans are known to bind to the complement receptor CR3. Between 25% and 38% of the mass comes from a covalently linked protein whose amino acid composition has been reported. Immunosuppressive acidic protein (IAP) levels have been reported to be elevated in cancer patients and correlated to cancer progression and prognosis. In some cases, this was linked to a positive immune response, but there may be other factors. Sci Rep. Aug 11 2016;6:29540. Gastric cancer is the most common malignancy diagnosed in Korea. Mol Med Rep 12 (5): 7629-36, 2015. Cui J, Chisti Y: Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production. In some parts of the world, mushroom extracts are often used by patients for their medicinal benefits. You might spot one of these colorful mushrooms, which can resemble a series of discs, growing out of the side of a hardwood tree. Those most frequently studied in cancer research are not usually sold in grocery stores. evidence) associated with each type of treatment is provided whenever Mushrooms can cause liver or kidney toxicity, says Narayanan. Torkelson, CJ, et al. Sometimes the active ingredient is removed and sold as a supplement. It's not commonly an indicator of cancer. The 3-year relapse-free survival rates were 76.2% in the PSK group and 47.8% in the UFT-only group (control), and the 3-year OS rates were 80.8% in the PSK group and 52.8% in the control group.[24]. These mushrooms have a disc-like shape and varying colors. Packed with antioxidants. This includes not only breast cancer, but lung, gastric, pancreatic and liver cancer as well. This summary is reviewed regularly and updated as necessary by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board, which is editorially independent of the National Cancer Institute (NCI). She is involved with integrative oncology outcome studies, including the Canadian/US Integrative Oncology Study . For cancer patients, the usual dose is 3g per day. Turkey tail is one of a variety of mushrooms that have been used for medicinal purposes for centuries in Asia. Mushrooms are a good source of antioxidants and vitamins, and they are low in calories. The message for patients is not to feel alone in this, and not to make a hasty decision, says Narayanan. Turkey tail is a woody bracket polypore fungus that grows on dead logs worldwide. Noting that hosts become immunocompromised at the time of tumor progression and that decreased expression of major histocompatibility complex (MHC) class I by the tumor is one mechanism that allows it to evade destruction by cytotoxic T lymphocytes, investigators conducted a retrospective study to evaluate the expression of MHC class I by immunohistochemical staining in the primary lesions of patients with stage II or stage III gastric cancer. [10-12] Most laboratory research studies have utilized G. lucidum products obtained via any of several extraction processes, which produce products that contain a mixture of two or more of these molecular species. Int J Mol Med 21 (5): 577-84, 2008. There were no differences between groups in 5-year RFS rates (52.7% in the PSK group and 52.7% in the control group) or 5-year OS rates (57.1% in the PSK group and 58.3% in the control group). Biotechnol Adv 21 (2): 109-22, 2003. Stamets spoke about powerful medical uses for mushrooms and their extracts, from anti-tuberculosis effects (Agarikon) to Cordyceps, a treasure trove of potential medicines, such as cyclosporine, which prevents organ . They compared its use alone versus a combination of Trametes versicolor and Ganoderma lucidum, or reishi mushroom. [13] The activity is considered to be immunomodulatory in nature, similar to many other medicinal fungi. After their analyses, the researchers concluded that the extract contributed to increased levels of cancer fighting cells in the immune system. [38] This finding led the investigators to conclude that ganoderenic acid B may have the potential to be developed into a multidrug resistance reversal agent. The authors concluded that PSK was effective as adjuvant immunotherapy for patients with gastric cancer and suggested that this improvement may well be both statistically and clinically significant. In fact, a 2008 review called for more research on the potential of turkey tail mushroom and its PSK for breast cancer. In addition, cytotoxic T cells increased in the peritumoral mucosa and normal mucosa within the radiation field in the PSK-treated group. You can learn more about how we ensure our content is accurate and current by reading our. Why do these multicolored mushrooms seem to hold so much promise? A quick look at cancer cell death is a perfect example. : DNA barcoding for identification of consumer-relevant mushrooms: A partial solution for product certification? Mycologia 96 (4): 742-55, 2004 Jul-Aug. Chen S, Xu J, Liu C, et al. Phase 1 clinical trial of Trametes versicolor in women with breast cancer. : Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. : Protein-bound polysaccharide K partially prevents apoptosis of circulating T cells induced by anti-cancer drug S-1 in patients with gastric cancer. Medicinal mushrooms have been used for hundreds of years, mainly in Asian countries, for treatment of infections. The mushroom is known for its anti-inflammatory, antibacterial, antioxidant, and anti-tumor properties that are essential for cancer treatment and prevention. editorially independent of NCI. So far, studies that have reported on the use of T. versicolor products in patients with breast cancer have focused on documenting changes in immune parameters (e.g., changes in T-cell subsets and B-cell numbers in blood) as opposed to clinical parameters (e.g., patient survival, resolution of symptoms/side effects, or improvement in quality of life). J Nat Med 69 (2): 198-208, 2015. A pancreatic mass is another name for a pancreatic tumor. Turkey tail (Coriolus versicolor) is a mushroom. Tsukagoshi S, Hashimoto Y, Fujii G, et al. They conclude, The evidence base for using mushrooms in cancer treatment has greatly increased.However, none of these studies recommend any mushroom extract as a standalone treatment. Look for a purified turkey tail supplement or turkey tail mushrooms from a reputable source. Turkey Tail Mushroom Dosage for Cancer. Last year, the FDA approved a $5.4 million Turkey Tail trial for cancer patients starting with approval for studying the use of a Turkey Tail extract in combination with chemotherapy for patients with advanced prostate cancer. Always follow the dosage instructions carefully. Added text to state that so far, studies that have reported on the use of T. versicolor products in patients with breast cancer have focused on documenting changes in immune parameters as opposed to clinical parameters (cited Wong et al. Complementary and Alternative Medicine (CAM): Treatment Options for Breast Cancer, What Are DIM Supplements? : 5-fluorouracil, mitomycin-C, and polysaccharide-K adjuvant chemoimmunotherapy for locally advanced gastric cancer: the prognostic significance of frequent perineural invasion. This combination may help cancer patients on a broader level. : Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Oncotarget 8 (6): 10071-10084, 2017. Turkey tail has a chewy texture and a strong flavor. The glycoprotein molecules are composed of a main chain beta-(1,4) glucan with beta-(1,3) and beta-(1,6)linked side chains. These results suggest that MAK may suppress the development of premalignant colorectal adenomas. The PSP and PSK in turkey tail mushroom might help slow cancer growth and boost the immune system. Last medically reviewed on March 25, 2020. Pancreatic cancer is the fourth leading cause of cancer deaths in men and women. Cochrane Database Syst Rev 6: CD007731, 2012. It has been associated with royalty, perhaps due to its rarity in the wild. The G. lucidum polysaccharides were isolated from a boiling water extract of G. lucidum fruit bodies by ethanol precipitation. One study found that PSP from turkey tail has prebiotic abilities and helps the gut regulate its balance of bacteria. Turkey tail mushroom enthusiasts note that these mushrooms have numerous properties that benefit your immune system. : Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. However, an author would be permitted to write a sentence such as NCIs PDQ cancer information summary about breast cancer prevention states the risks succinctly: [include excerpt from the summary].. Oncol Rep 25 (1): 267-72, 2011. : Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18). J Med Food 8 (2): 159-68, 2005. At TEDMED, TEDTalks favorite Paul Stamets gave an emotional talk about new medical uses for mushrooms including a variety that, he says, helped treat his mother's cancer. This systematic review and meta-analysis draw from randomized, placebo-controlled, double-blind trials to assess the efficacy of Yun Zhi (YZ) for survival in cancer patients. Interested in learning about other natural treatments for cancer and cancer prevention? These designations are intended to help readers assess the strength of the evidence supporting the use of specific interventions or approaches. Permission to use images outside the context of PDQ information must be obtained from the owner(s) and cannot be granted by the National Cancer Institute. Some studies show mushrooms boost parts of the immune system that are linked to cancer. Hennicke F, Cheikh-Ali Z, Liebisch T, et al. In: Baars JJP, Sonnenberg ASM, eds. Integr Cancer Ther. Many people still prefer this option. However, some milder adverse effects may include: Anyone with an underlying health condition should consult a doctor before trying any new supplement, including turkey tail extract. : Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team. [4-6] Polysaccharide-K (PSK) or krestin, from the mushroom T. versicolor, is an approved mushroom product used for cancer treatment in Japan. Want to use this content on your website or other digital platform? Oka S, Tanaka S, Yoshida S, et al. People use turkey tail . : Reishi Mushroom: Ganoderma Lucidum: Standards of Analysis, Quality Control, and Therapeutics. Data from the 15 preclinical studies supported the anticancer effects of PSK by way of immunomodulation and potentiation of immune surveillance. One other large study not included in this meta-analysis was a Japanese multicenter comparative trial of adjuvant chemotherapy versus adjuvant chemotherapy and PSK involving 751 patients undergoing curative resection, conducted from 1978 to 1981. Miller R, Galitsky NM, Duax WL, et al. Clinical trials in cancer patients have demonstrated that G. lucidum products are generally well tolerated.[1]. The scientific name of turkey tail is Trametes versicolor (L.) Lloyd, although it has been known by other names, notably Coriolus versicolor (L. ex Fr.) More information about contacting us or receiving help with the Cancer.gov website can be found on our Contact Us for Help page. Xia Q, Zhang H, Sun X, et al. Coriolus is a multicolored fungus that grows wild in various parts of the world and in the United States. Gao Y, Tang W, Dai X, et al. Some people like to chop dried turkey tail mushrooms and steep them to make tea, while others use them in cooking. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Complementary Medicine / Alternative Medicine, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/, https://www.cancer.org/cancer/breast-cancer/about/how-common-is-breast-cancer.html, https://link.springer.com/chapter/10.1007/978-981-13-6382-5_7, https://www.mdpi.com/1422-0067/18/9/1934/htm, https://www.cancer.org/cancer/colon-rectal-cancer/about/key-statistics.html, https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201801231, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687673/, https://www.cancer.gov/about-cancer/treatment/cam/hp/mushrooms-pdq, https://www.tandfonline.com/doi/full/10.4161/gmic.29558, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351938/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367522/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592279/, https://journals.sagepub.com/doi/full/10.1177/1534735416649034, https://www.ncbi.nlm.nih.gov/pubmed/22204346, https://www.hindawi.com/journals/isrn/2012/251632/, https://www.poison.org/articles/2009-jun/wild-mushroom-warning, New clues to slow aging?
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